Here you go:

Many of us are familiar with Preparation H for its use in treating hemorrhoids. But did you know that Preparation H is also used to fight wrinkles and relieve puffy eyes?

The ’secret’ ingredient in Preparation H is Bio-dyne, also known as Live Yeast Cell Derivative – LYCD. This formulation is found only in the Preparation H marketed in Canada and not in the US version. Preparation H Cream found in the USA does not contain biodyne, which was removed when the product was reformulated years ago. Instead, it contains phenylephrine HCI 0.25 % – a vasoconstrictor (shrinks vessels) that some dermatologists claim will constrict capillaries and temporarily reduce dark circles and puffy eyes. However, many individuals report irritation and burning when using the US version of Preparation H.
Preparation H for wrinkles and puffy eyes article | Pharmacymix.com, Skin Care Pharmacy and Blog Specializing in Anthelios and Mexoryl Sunscreens

Only in Canada...